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A sheltered life

jeudi 11 octobre 2012, par Damien F. Meyer

© Damien F. Meyer

Molecular mechanisms to manipulate host processes

We are investigating the role of the Type IV Secretion System of E. ruminantium in bacterial adaptation to the host cell. We want to know how it is expressed along developmental cycle of E. ruminantium between strains of various virulence.
We developed S4TE, a bioinformatic tool in Perl to predict Type IV Secreted Effector proteins of E. ruminantium and to analyse their genomic context. Using molecular and cell biology tools, we are characterizing the function of these effectors.

S4TE website


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